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Journal of Health Psychology, Vol. 12, No. 3, 417-430 (2007)
DOI: 10.1177/1359105307076230
© 2007 SAGE Publications

Assessing Developmental Outcomes in Children from Kilifi, Kenya, Following Prophylaxis for Seizures in Cerebral Malaria

Amina Abubakar

Centre for Geographic Medicine Research, Coast, Kemri, Kenya and Tilburg University, The Netherlands, A.AbubakarAli{at}uvt.nl

Fons J.R. Van De Vijver

Tilburg University, The Netherlands and North-West University, South Africa

Sadik Mithwani

Centre for Geographic Medicine Research, Coast, Kemri, Kenya

Elizabeth Obiero

Centre for Geographic Medicine Research, Coast, Kemri, Kenya

Naomi Lewa

Centre for Geographic Medicine Research, Coast, Kemri, Kenya

Simon Kenga

Centre for Geographic Medicine Research, Coast, Kemri, Kenya

Khamis Katana

Centre for Geographic Medicine Research, Coast, Kemri, Kenya

Penny Holding

Centre for Geographic Medicine Research, Coast, Kemri, Kenya and University of Oxford, UK

The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function.

Key Words: assessment • cerebral malaria • Kenya • prophylaxis • seizures


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