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Journal of Health Psychology
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Psychological Correlates of Mental Stress-induced Ischemia in the Laboratory

The Psychophysiological Investigation of Myocardial Ischemia (PIMI) Study

Mark W. Ketterer

Henry Ford Hospital/CFP3, 2799 West Grand Boulevard, Detroit MI 48202, USA. [Fax 313–916–8846; Tel. 313–916–2523]

Kenneth E. Freedland

David S. Krantz

Peter Kaufmann

Sandra Forman

Anthony Greene

James Raczynski

Genell Knatterud

Kathy Light

Robert M. Carney

Peter Stone

Lewis Becker

David Sheps

Participants consisted of 184 patients (160 males, 24 females) with positive angiograms or prior myocardial infarctions who displayed at least 1 mm of ST segment depression on a standardized treadmill test. Mean scores on the Reward Dependence subscale of the Tridimensional Personality Questionnaire were higher in patients displaying ischemia during mental stress. Patients who reported higher levels of irritability/anger in response to the Speech stressor were also more likely to display ischemia. However, this result was primarily a result of the females in the sample whose ratings of interest and irritability were associated with ischemia during the Speech task. Psychometric measures previously found in prospective studies to predict acute cardiac events were unrelated to mental stress-induced ischemia in the laboratory.

Key Words: anger • ischemia • mental stress

Journal of Health Psychology, Vol. 5, No. 1, 75-85 (2000)
DOI: 10.1177/135910530000500112
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